Papers

Selected references from our lab :

- Pyramidal neurons generated from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Espuny-Camacho I, Michelsen, K, Hasche A, Bali C, Gall D, Bilheu A, Herpoel A, Gaspard N, Schiffmann SN, Gaillard A, and Vanderhaeghen P. Neuron (2013), in press.

- BCL6 induces neurogenesis through Sirt1-dependent epigenetic repression of selective Notch transcriptional targets. Tiberi, L., van den Ameele, J., Dimidschstein, J., Piccirilli, J., Gall, D., Herpoel, A., Bilheu, A., Bonnefont, J., Iacovino, M., Kyba, M., Bouschet T., and Vanderhaeghen P. Nature Neurosci. (2012), 15, 1627-1635.

- Generation of Cortical Neurons from Embryonic Stem Cells. Gaspard N, Bouschet T, Herpoel A, Naeije G, vandenAmeele J, and Vanderhaeghen P. Nature Protocols 4 (2009), 1454-63. (PDF)

- Wnts blow on NeuroD to promote adult neuron production and diversity. Vanderhaeghen P. Nature Neurosci. 9 (2009), 1079-1081. (PDF)

- Making Cortex in a Dish: corticopoiesis from embryonic stem cells. Gaspard N, Gaillard A, and Vanderhaeghen P. Cell Cycle 8 (2009), 2491-6. (PDF)

- Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of mammalian striatum. Passante L, Gaspard N, Degraeve M, Frisén J, Kullander K, De Maertelaer V, Vanderhaeghen P. Development. 135 (2008), 3281-3290 (PDF)

- An intrinsic mechanism of corticogenesis from embryonic stem cells. Gaspard N, Bouschet T, Hourez R, Dimidschstein J, Naeije G, van den Ameele J, Espuny-Camacho I, Herpoel A, Passante L, Schiffmann SN, Gaillard A, Vanderhaeghen P. Nature 455 (2008) 351-357 (PDF)

- An RNA gene expressed during cortical development evolved rapidly in humans. Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M, Vanderhaeghen P, and Haussler D. (2006).
Nature 443 (2006),167-172. (PDF)

- Genetic Analysis of EphA-Dependent Signalling Mechanisms Controlling Topographic Mapping in Vivo. Dufour A, Egea J, Kullander K, Klein R, and Vanderhaeghen P.
Development 133 (2006), 4415-4420. (PDF)

- Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Depaepe V, Suarez N, Passante L, Dufour A, Gorski J, Jones K, Ledent C, and Vanderhaeghen P.
Nature 435 (2005), 1244-1250. (PDF)

- Mapping labels in the developing human visual system and the evolution of binocular vision. Lambot M-A, Depasse F., Noel J-C, and Vanderhaeghen P.
J. Neurosci. 25 (2005), 7232-7237. (PDF)

- Regulation of EphA4 Kinase Activity Is Required for a Subset of Axon Guidance Decisions Suggesting a Key Role for Receptor Clustering in Eph Function. Egea J, Vig Nissen U, Dufour A, Sahin M, Greer P, Kullander K, Mrsic-Flogel T, Greenberg ME, Kiehn O, Vanderhaeghen P, Klein R.
Neuron 47 (2005),515-528. (PDF)

- Developmental Mechanisms of Thalamocortical Patterning: Intrinsic, Extrinsic, and in Between. Vanderhaeghen P, and Polleux F.
Trends Neurosci. 27 (2004), 384-391. (PDF)

- Area-Specificity and Topography of Thalamocortical Projections Controlled by Ephrin/Eph genes. Dufour A, Seibt J, Passante L, Depaepe V, Ciossek T, Frisen J, Kullander K, Flanagan J, Polleux F, and Vanderhaeghen P.
Neuron 39 (2003), 453-465. (PDF)

- Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Seibt J, Schuurmans C, Gradwhol G, Dehay C, Vanderhaeghen P, Guillemot F, and Polleux F.
Neuron 39 (2003), 439-452. (PDF)